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  • HPLC Troubleshooting

HPLC Troubleshooting

It’s time-consuming and expensive when things go wrong in the lab. Our scientists have gathered loads of experience through prior experience working in labs and alongside our customers. We know what to do when things go wrong! If you’re in a bind, our technical team are always on hand to help.

We’ve also harnessed this know-how into a series of articles centred around HPLC troubleshooting. A solution is often closer than you think.

If you would like insights sent straight to your inbox, sign up for our mailing list.

  • Investigating (and solving) robustness issues in HPLC

  • Ghost Peaks in Gradient HPLC

  • Peak Tailing in HPLC

  • Causes of Retention Time Drift in HPLC

  • System and Column Volumes in HPLC - we still haven’t got the message!

  • Retention Shifts in HPLC

  • Polar analyte retention and phase collapse

  • Retention Time Variability in HPLC

  • Troubleshooting HPLC Separation Issues - Are checklists only for pilots?

  • HPLC Noisy Baselines

  • HPLC Troubleshooting Filtration

In This Section :

  • Investigating (and solving) robustness issues in HPLC
  • Ghost Peaks in Gradient HPLC
  • Peak Tailing in HPLC
  • Causes of Retention Time Drift in HPLC
  • System and Column Volumes in HPLC - we still haven’t got the message!
  • Retention Shifts in HPLC
  • Polar analyte retention and phase collapse
  • Retention Time Variability in HPLC
  • Troubleshooting HPLC Separation Issues - Are checklists only for pilots?
  • HPLC Noisy Baselines
  • HPLC Troubleshooting Filtration
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