Primesep Acidic

Primesep Acidic HPLC Column Guards from SiLEC

Primesep columns are different in the degree they retain ionic compounds. Neutral compounds are retained on all columns similarly. Primesep A, 100, 200 and 300 are cation exchange columns with different strengths of embedded functional groups.  Primesep N is a normal-phase analytical column with embedded acidic groups with a pKa of about 5.  This phase improves retention of basic compounds by a cation-exchange mechanism at pH > 5 and can separate polar compounds by the HILIC mechanism.