YMC-Pack Diol

YMC-Pack Diol Analytical HPLC Columns

The silica-based YMC-Pack Diol is a rugged and efficient normal phase, reversed phase or size exclusion material. It is generally used for the separation of biomolecules and pharmaceuticals. As the non-specific adsorptive sites have been eliminated it exhibits better performance characteristics for size separations than nonbonded silica.

    YMC-Pack Diol is available in four tightly controlled porosities and is, therefore, suitable for separation and molecular weight determination of a wide range of peptides, proteins, oligonucleotides, carbohydrates and other biopolymers with molecular weights of approx 200 to several hundred thousand.

YMC-Pack Diol

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Features
  • Applicable to proteins, peptides, carbohydrates and nucleic acid components
  • 2 µm for UHPLC
  • Scalability from 2 or 3 µm to 20 µm
  • Reproducibility with minimal secondary interactions
Specifications
  YMC-Pack Diol-60 YMC-Pack Diol-120 YMC-Pack Diol-200 YMC-Pack Diol-300
Suitable for carbohydrates and peptides intermediate proteins large proteins
very large proteins/
monoclonal antibodies
Recommended MW range <10,000 Da
1,000 –
100,000 Da
5,000 –
300,000 Da
20,000 –
1,000,000 Da
Pore size 6 nm / 60 Å 12 nm / 120 Å 20 nm / 200 Å 30 nm / 300 Å
Particle size 3, 5 µm 3, 5 µm 2, 3, 5 µm 2, 3, 5 µm
Surface area 650 m2/g 330 m2/g 175 m2/g 100 m2/g
Recommended pH Range 5 - 7.5
Literature