Zorbax Extend

Zorbax Extend-C18 HPLC Columns from Agilent Technologies

Extend-C18 columns incorporate a unique patented bidentate silane, combined with a double-endcapping process that protects the silica from dissolution at high pH - up to pH 11.5. Columns are best applied for separations of compounds that are either (1) basic and have little or no retention at low or intermediate pHs, (2) more stable or more soluble at high pH, or (3) basic and show poor peak shape at low or intermediate pH.

Zorbax Extend All pictures shown are for illustration purpose only. Actual product may vary.

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Features
  • High efficiency and long life at high pH - up to pH 11.5
  • Unique bidentate bonding and double endcaping provides high pH stability
  • More efficiency and better peak shape than polymer-based columns
  • Improve retention, resolution and peak shape of basic compounds
  • High sensitivity for LC/MS separations of peptides and proteins
Specifications
  Pore Size Surface Area Temp Limits* pH Range** Endcapped Carbon Load USP Designation
ZORBAX Extend C18 80 Å 180 m2/g 60 ºC 2 - 11.5 Double 12.5% L1

Specifications represent typical values only.
*Temperature limits are 60 °C up to pH 8, 40 °C from pH 8-11.5.
**Above pH 6 highest column stability for all silica based columns is obtained by reducing the operating temperature to 40 ºC or below and using lower buffer concentrations (0.01-0.02M) or organic buffers.

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